|
Cu(II)-ProIAPP1-48 Ratio |
0.0 |
0.5 |
1.0 |
2.0 |
5.0 |
10.0 |
|
ProIAPP1-48 Only 24h 21d |
10( 2.6) 42(12.8) |
13(2.2) 29(3.3) |
6(5.2) 8(3.1) |
4(2.0) 5(1.5) |
0(0.0) 0(0.0) |
0(0.0) 0(0.0)
|
|
ProIAPP1-48 + Al(III) 24h 21d |
46(21.5) 75(23.2) |
7(1.5) 12(0.7) |
5(3.7) 13(3.8) |
4(0.3) 5(0.5) |
1(0.2) 5(2.0) |
5(1.1) 5(0.5)
|
|
ProIAPP1-48 + Zn(II) 24h 21d |
14( 1.9) 36( 3.4) |
8(0.6) 17(8.3) |
6(3.9) 12(5.4) |
1(0.8) 8(2.8) |
0(0.0) 1(0.2) |
3(3.7) 0(0.0)
|
Table 1. The influence of the ratio of Cu(II) to ProIAPP1-48 on ThT fluorescence of 20 mM ProIAPP1-48 in the absence and presence of 200 mM Al(III) or Zn(II) after 24h or 21 days. Mean and SD are given , n=3.