Cu(II)-ProIAPP1-48 Ratio

0.0

0.5

0.75

1.0

1.5

2.0

ProIAPP1-48 Only      

                               

50(  7.4)

  9(1.4)

  9(0.9)

5(0.6)

4(0.5)

2(0.7)

ProIAPP1-48 + Al(III)

                                

58(12.0)

13(4.0)

13(2.4)

8(1.5)

6(1.7)

8(1.6)

ProIAPP1-48 + Zn(II) 

                               

26(  1.7)

  6(1.2)

  3(1.6)

5(2.3)

3(2.0)

2(2.3)

Table 2. The influence of the ratio of Cu(II) to ProIAPP1-48 on ThT fluorescence of 20 mM ProIAPP1-48 in the absence and presence of 200 mM Al(III) or Zn(II) after incubation for 7 days. Mean and SD are given , n=3.

 

Exley et al.Journal of Diabetes Research and Clinical Metabolism  2012 1:3DOI : 10.7243/2050-0866-1-3