Figure 1 : Lower rate of change in plasma Apo A-II monomer over gestational time in GDM than controls by mass spectrometry.


(A) Spectra are shown for a single representative GDM patient and age-matched control at gestational age range 16-22 weeks. Apo A-II monomer was identifiable at 8811 Da. Arrows denote peaks corresponding to Apo A-II monomers. CTL, age-matched controls; GDM, gestational diabetes mellitus(B) Quantification of median spectral intensities by SELDITOF mass spectrometry for n=4-5 GDM subjects and n=8 age-matched controls at each gestational age for Apo A-II monomer. Error bars denote 95% confidence intervals.
*, p<0.05 by Mann-Whitney U test relative to 4-12 weeks.

Ippolito et al.Journal of Diabetes Research and Clinical Metabolism  2013 2:22DOI : 10.7243/2050-0866-2-22