Table 1 : Methylation and metabolic measures.


Measure Rural Urban Rural Urban Urban RISC
  Hyderabad Hyderabad Lucknow Lucknow Indian RISC

  n Median n Median n Median n Median n Median n Median
    (IQR)   (IQR)   (IQR)   (IQR)   (IQR)   (IQR)

(%) ADCY5 63 96.6 66 96.8 83 96.7 89 96.7 155 96.8 332 90.5
Methylation - (96.0-97.0) - (96.3-97.0) - (96.4-97.3)   (96.2-97.3) - (96.0-97.0)   (89.4-91.2)
(%) FTO 80 8.0 80 8.0 89 8.5 90 8.7 170 8.5 336 5.8
Methylation - (6.9-9.2)   (6.7-9.1)   (7.8-10.0)   (7.8-9.7) - (7.5-8.5) - (5.3-6.3)
(%) KCNJ11 78 96.0 79 96.2 88 95.5 86 95.7 165 95.8 337 94.3
Methylation - (95.5-96.7) - (95.5-96.5) - (95.1-95.8)   (95.2-96.0) - (95.3-96.3) - (93.8-94.8)
Age 91 46 91 47 91 45 91 46 182 46 351 44
(years) - (41-52) - (42-51) - (41-50) - (43-50) - (42-50.5)   (38-51)
Sex(% male) 91 52% 91 52% 91 77% 91 77% 182 64% 351 43%
Fasting glucose 91 4.94 91 5.05 91 5.22 91 5.55 182 5.18 350 5.15
(mmol/L) - (4.66-5.16) - (4.72-5.27) - (4.76-5.80) - (4.94-6.27) - (4.83-5.72) - (4.80-5.50)
Fastinginsulin 91 3.80 91 6.00 91 5.00 90 6.75 181 6.20 348 4.61
(mU/L) - (1.90-8.20) - (3.0-10.0) - (2.0-6.8) - (4.2-10.5) - (3.7-10.0) - (3.02-6.33)
HOMA-IR 80 0.84 76 1.34 84 1.03 74 1.52 150 1.44 347 1.07
  - (0.39-1.70) - (0.56-2.13) - (0.47-1.59) - (0.96-2.42) - 0.76-2.27) - (0.66-1.54)
BMI 91 23.40 91 25.98 91 20.90 91 25.00 182 25.47 351 24.50
(Kg/m2) - (20.8-25.8) - (23.3-27.4) - (18.2-24.0) - (22.6-27.6) - (22.9-27.5) - (23.0-27.8)
Total cholesterol 91 4.68 91 4.68 91 4.60 90 4.78 181 4.73 348 4.90
(mmol/L) - (3.93-5.45) - (4.03-5.50) - (3.82-5.37) - (4.03-5.58) - (4.03-5.53) - (4.30-5.40)
LDL 90 2.86 91 2.93 90 2.63 90 2.73 181 2.83 345 2.90
(mmol/L) - (2.25-3.57) - (2.19-3.62) - (2.06-3.32) - (2.18-3.70) - (2.19-3.62) - (2.40-3.50)
HDL 91 1.09 91 1.14 91 1.21 90 1.21 181 1.19 348 1.40
(mmol/L) - (0.96-1.29) - (0.56-1.37) - (1.03-1.47) - (1.03-1.40) - (0.98-1.40) - (1.19-1.65)
Triglycerides 91 1.36 91 1.41 91 1.32 90 1.57 181 1.46 348 0.93>
(mmol/L) - (1.07-1.92) - (1.06-2.04) - (0.92-1.90) - (1.22-2.14) - (1.13-2.05) - (0.68-1.25)

R. Elliott et al.Journal of Diabetes Research and Clinical Metabolism  2013 2:6DOI : 10.7243/2050-0866-2-6