Table 6 : The absolute amount of amino acids appearing in the first day urine after different treatments*, †, ‡.

AA †Group No. /mg amino acid /mL urine
1 2 3 4 5 6 7 8
Control AAM QT AAM +QT DM DM+ AAM DM+ QT DM+ AAM+QT
Gly 1.4±0.1 4.1±0.1& 0.2±0.1& 4.6±0.2& 21.4±0.2& & 13.7±0.2& &∂ 3.9±0.2&∂ 4.2±0.1&∂
Val 0.7±0.1 3.6±0.2& 0.2±0.1& ND 2.6±0.1& 2.5±0.2& 2.7±0.1& 3.1±0.2&∂
Leu 4.4±0.2 6.0±0.2& 0.3±0.0& 11.3±0.2& 6.6±0.2& 6.2±0.2& 2.7±0.1&∂ 11.3±0.4&∂
Ile 0.7±0.1 ND 0.3±0.0& 1.2±0.3& 0.5±0.1& 8.2±0.2&∂ 1.3±0.0&∂ 11.4±0.4&∂
Ser 12.0±0.2 ND ND ND ND ND ND ND
Phe 3.9±0.1 2.4±0.1& 0.2±0.0& 7.9±0.2& 2.0±0.1& 1.5±0.1& 1.7±0.1& # 2.9±0.1&∂
Met 6.2±0.2 3.9±0.1& 35.4±0.3& & & 2.5±0.2& 5.9±0.1 2.1±0.1& 23.1±0.3& & 3.6±0.1&∂
Trp 1.2±0.2 1.7±0.1& 0.1±0.0& & 1.8±0.1& 2.1±0.1& 1.7±0.1& 0.2±0.1&∂ 3.4±0.1&∂
Arg 0.6±0.2 6.9±0.2& 0.1±0.0& 2.4±0.0& ND 0.8±0.1 0.1±0.0&∂ 1.9±0.1&∂
Lys 3.3±0.1 1.0±0.0& 0.3±0.1& 4.4±0.1& 2.9±4& 1.2±0.1&∂ 0.3±0.0&∂ 5.8±0.2&∂
His 0.7±0.1 6.5±0.1&  ND ND  ND 0.6±0.1 0.1±0.0& 1.9±0.0&
Sum 35.1 36.1 37.1 36.1  43.1 38.5 35.0 49.5
TAA(mg/d) 1580 3249  2003 3791 8491 6584 6545 8910

*Measured on urine collected the first day after different treatments.
†Data expressed in mean±SD (n=8). The superscript symbol "&" in the same row indicate significant difference
from the normal control. "&" for p<0.05; "&&" for p<0.01; "&&&" for p<0.001. The superscript symbol "∂" in
the same row indicates significant difference among the DM-related groups taking the DM rats as the reference
(p<0.05). Dose: ip Moriamin 1.6 mL/rat-day. QT ip treated control (70 mg/kg-day, suspended in PBS).
‡Sum: sum of amino acid in per mL (mg/mL).
TAA: total amino acid excreted per day (mg/24 h)
ND: not detected

Chen et al.Journal of Diabetes Research and Clinical Metabolism  2014 3:5DOI : 10.7243/2050-0866-3-5