Journal of Diabetes Research & Clinical Metabolism

Journal of Diabetes Research & Clinical

ISSN 2050-0866
Original Research

Determinants of loss of glycemic control in patients with type 1 diabetes mellitus. Prospective cohort study from Iraq

Abbas Ali Mansour1†*, Ahmed AAl-Maliky2† and Bashar Kasem2†

*Correspondence: Abbas Ali Mansour

These authors contributed equally to this work.

1. Department of Medicine, Basrah College of Medicine, Basrah, Iraq.

Author Affiliations

2. Department of Medicine, Al-Faiha Hospital, Basrah, Iraq.


Background: Despite advances in insulin therapeutics during the past 25 years, only a few individuals with type 1 diabetes achieve glycemic control. The aim of this study is to assess the determinants of loss of glycemic control in patients with type 1 diabetes mellitus in Basrah, Iraq.

Methods: The data presented are derived from the Al-Faiha Diabetes Endocrine and Metabolism Center (FDEMC) in Basrah. Eligible patients were those with type 1 diabetes. Follow-up started from August 2008 to the end of February 2012. Seven hundred and forty one patients completed the study.

Results: Deterioration of glycemic control was seen in 42.8%. Those who achieved age group specific target HbA1c were 12.4%. Those with worse glycemic control are younger age (21.0±10.4 vs. 23.1±10.9; p=0.01) ,have lower education level (9.45±2.0 vs. 11.75±2.6; P=0.01).) and lower baseline HbA1C percent (9.45±2.048 vs. 11.75±2.619; p <0.0001) than those with more optimal glycemic control.

Conclusion: Factors contributing to worse glycemic control were lower age, less education level, and lower baseline HbA1c. Factors that do not contribute to loss of glycemic control are: gender, number of visits, urban/rural, family history, duration of diabetes, self-monitoring of blood glucose (SMBG) use, Body mass index (BMI) or use of pen for insulin delivery.

Keywords: Type 1 diabetes mellitus, glycemic control, HbA1c

ISSN 2050-0866
Volume 2
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