Figure. 1 Schematic model of DSB repair processed by HR and SSA repair pathways. After the DSB is induced by radiation, the HR and SSA repair pathways start the repair process with MRN, RPA, Phosphorylated-RPA (P-RPA), and Rad52 proteins (Common starting steps is panel A and panel B). The repair process continues with either panel A) Rad54 mutated cell line, or panel B) Rad51 mutated cell line using Ercc1/ Xpf and ligase III proteins.

Nikjoo et al.Journal of Molecular Engineering and Systems Biology  2012 1:1DOI : 10.7243/2050-1412-1-1