Table 1  - Functional associations of M. pneumoniae subnets

Subnets produced by Netsplitter partitioning and subsequent merging, compared to pathway assignments made by Yus [5] et al . Abbreviations for metabolite names are taken from [5] and a listing with full names is available as supplementary material to that work.

Subnet

Internal metabolites

Function

1

Ade, Ado, SAH, SAM

Methionine

2

NACD, dNAD

Nicotinate

3

CBP,Cir

Arginine fermentation

4

RIB, R5P, dRu5P, E4P, S7P

Pentose phosphate

6

AC-P, AcAld, AcCoA, dR5P, Lia, DHLA, SAcDHLiA

Pyruvate;

Lipoamide

7

Guo, Gua, dATP, dGTP, 2GP, 3GP, dAMP, dADP, dGMP, dGDP, NADP+, NADPH, redThio, oxThio, CDP,  DGP, GDP, GMP, GTP

Purine nucleotides

8

GLY, DHA, DHAP, Mt1P, G6P, M6P, 3dG6P, FBP, A6P, GA, F1P, proHis, pro-NpPHis

Glycolysis;

Carbohydrates; Ascorbate

12

Ado3,5P, dPCoA, PC, pGLY, UDP-GAL, 1aG3P, ACP, ACP-R, apoACP, CDP-DAG, CHO, DAG, FA, G3PC, PAC, PAN4P, pG3P, snG3P, UDP-GLC, UTP

Lipids;

Choline;

CoA

13

Asp, Glu

Amino acid

14

THF, 10fTHF, dTTP, Ser, UMP, Ura, Urd, Cyd, dCMP, dCyd, DHF, dTDP, dTMP, dUMP, dUrd, FOR, Thd

Pyrimidine nucleotides;

Folate

FMN

FMN

Riboflavin

TPS

TPS

Thiamine

Wynand S Verwoerd Journal of Molecular Engineering and Systems Biology  2012 1:2DOI : 10.7243/2050-1412-1-2