Original ResearchOpen Access
Alveolar macrophages from patients with tuberculosis exhibit reduced capacity of restricting growth of Mycobacterium tuberculosis: a pilot study of vitamin D stimulation in vitroPersson H. Lennart, Eklund D, Larsson M, Welin A, Paues J, Idh J, Fransson SG, Stendahl O, Lerm M, SchÃ¶n T
Applied Scientific Reports 2013 1 : 6 ( 15 April 2013 )
Short reportOpen Access
Antimicrobial resistance patterns in extended-spectrum β-lactamase producing Escherichia coli and Klebsiella pneumoniae isolates in a private tertiary hospital, KenyaDaniel Maina, Paul Makau, Andrew Nyerere, Gunturu Revathi
Applied Scientific Reports 2013 1 : 5 ( 3 April 2013 )
The aim of introducing this section is to focus on bacterial response to adverse conditions and external stimulus. The scope of this section focuses on cell communication - quorum sensing, through biochemical signalling pathways like two-component signal transduction, and anti quorum sensing treatments.This section also focuses on infectious disease caused by biofilms like catheter infections, dental plaque, gingivitis, middle ear infections, urinary tract infections, endocarditis.
Scope of this section includes disease mechanism, mode of transmission, host-pathogen interactions, causal microorganisms, viral diseases, zoonotic diseases, bacterial diseases, Tuberculosis and non tuberculosis mycobacterial disease, other pathogenic diseases. This section also includes clinical microbiology after diagnosis of the disease, host drug resistance and susceptibility, multi drug resistance, new drug targets, immunotherapy and epidemiology.
This section focuses on the genetic architecture of microorganisms like gene expression, mutation, post genomic approaches such as transcriptomic analysis, and bacterial reproduction. The importance of the section also includes human microbiome, target gene sequencing, pyrosequencing, metegenomics and RNA - protein based other techniques.
This special section covers microbial application in various industries and their products such as fermented food products, chemicals, pharmaceutical products, bio fuels, and catalysts. The scope of section also concentrates on food microbiology, the study of microbial physiology with respect to environment that includes bioremediation, waste water treatment, and leaching.