Figure 1 : Effect of treatment with a combination of Tam and Dox on cell proliferation in breast cancer cells.

BT483, MDA-MB-231, 231eB and 231neo cells were cultured in DMEM supplemented with 10% fetal calf serum for 24h. After culturing for 24-h, cells were treated with different concentrations of Dox and Tam for 48h. Cell growth inhibition was determined by MTT assay. The combination of Tam and Dox was more effective than either agent alone: * P< 0.05.

Huang et al.Journal of Pharmaceutical Technology and Drug Research  2013 2:12DOI : 10.7243/2050-120X-2-12