Table 2 : Plackett-Burman experimental design with 11 variables and 2 levels.


Experiment # X1 X2 X3 X4 X5 X6 X7 X8 X9 X10 X11

1 + + + + + +
2 + + + + + +
3 + + + + + +
4 + + + + + +
5 + + + + + +
6 + + + + + +
7
8 + + + + + +
9 + + + + + +
10 + + + + + +
11 + + + + + +
12 + + + + + +

*Presence of excipients is identified by “+”.
Absence of excipients is identified by “−”.

Maltais et al.Journal of Pharmaceutical Technology and Drug Research  2015 4:2DOI : 10.7243/2050-120X-4-2