Table 1 : Oscillation stress sweep: yield stress and stress flow values of the two tested batches of formulation A and
B at room temperature (25°C) and body temperature (37°C).


    G’ (Pa) G’’ (Pa) σy (Pa) σf (Pa) tan δ δ (°)

Formulation A 25°C Batch  A1 5.64 ± 0.004  2.73 ± 0.002 1.30 5.3 0.48 ± 0.001 25.8 ± 0.05
Batch  A2 5.62 ± 0.004 2.81± 0.001 1.30 5.3 0.49 ± 0.001 26.3 ± 0.07

Formulation B 25°C Batch  B1 0.33 ± 0.020 0.69 ± 0.003 0.50 - 2.02 ± 0.019 63.7± 1.08
Batch  B2 0.23 ± 0.020 0.64± 0.002 0.50 - 2.82 ± 0.020 70.5 ± 1.14

Formulation A 37°C Batch  A1 4.27 ± 0.002 2.49 ± 0.001 1.00 4.2 0.57 ± 0.001 30.0± 0.03
Batch A2 4.64 ± 0.002 2.83 ± 0.007 1.00 4.2 0.60 ± 0.001 30.8 ± 0.04

Formulation B 37°C Batch  B1 0.19 ± 0.010 0.45 ± 0.003 0.25 - 2.44± 0.021 67.7 ± 1.20
Batch  B2 0.12 ± 0.007 0.39± 0.002 0.25 - 3.13± 0.020 72.3 ± 1.14

Demma et al.Journal of Pharmaceutical Technology and Drug Research  2018 7:1DOI : 10.7243/2050-120X-7-1