1. Department of Environmental and Occupational Health, USF College of Public Health, Tampa, Florida, USA.
2. Institute of Microbiology and Virology, Almaty, Kazakhstan.
4. Florida Hospital, Tampa, Florida, USA.
Increasing antibiotic resistance among multidrug resistant pathogens necessitates the search for newer antimicrobials. Streptomyces historically produce the largest number of antibacterials and herein we describe isolation of antagonists from extremophiles using unusual culture media. Antagonists or antimicrobials produced under extremophile environmental conditions demonstrated activity against MRSA from Kazakhstan and the United States.
Keywords: Extremophiles, antagonists, antibacterial, antibiotics, HA-MRSA