Mesenchymal stem cells

Journal of Regenerative Medicine & Tissue Engineering Open access Journal covers special section Mesenchymal stem cells are stromal cells that are mutipotent which can differentiate into any cell types. This Special section highlights on every aspect of stem cell research like developing methodologies for isolating and culturing MSC'S, Tissue grafting, homing mechanisms, host immune response to implanted cells. It also includes the use of mesenchymal stem cells in the treatment of disorders like cardiovascular diseases, bone and cartilage repair, spinal cord injury and autoimmune diseases.

Immunomodulation and clinical trials

MSCs also possess the ability to impart profound immunomodulatory effects, which remain largely unknown. Mesenchymal stem cells have been explored as a new clinical approach aimed at immune-mediated disease and provides their potential for clinical use and cell-based therapy for immune-mediated disorders, Drug Delivery for Immunomodulation.
Editors
Aline M. Betancourt, Tulane University School of Medicine, USA
Ronald James Neufeld, Queen’s University, Canada
Rouel S. Roque, Roseman University of Health Sciences, USA
Mark Weiss, Kansas State University, USA

Bone Mesenchymal stem cells

Bone marrow was the primary resource reported to contain Mesenchymal stem cells. These provide micro environmental assistance for hematopoietic stem cells (HSCs), and have the ability to differentiate into various mesodermal lineages. For MSC isolation and characterization several methods are used the common isolating technique include the ability of the MSCs to selectively adhere to plastic surfaces and characterized by immunocytochemical detection or fluorescence-activated cell sorting (FACS).
Editors
A. Mantalaris, Imperial College London, UK
Michael Hadjiargyrou, New York Institute of Technology, USA
Jin Nam, University of California-Riverside, USA

Gene engineering

Genetic engineering is the development by which scientists transform the genome of an organism which includes stem cell therapy or gene therapy. These therapies incorporate Mesenchymal stem cells that have the ability to differentiate into various cell types. Gene therapy aims for treating Cardiovascular Disease, Neurological Disease, Bone formation, renal failure, regeneration and repair.
Editors
Warren L. Grayson, Johns Hopkins University , USA
Liisa Tiina Kuhn, University of Connecticut Health Center, USA
Subhas C. Kundu, Indian Institute of Technology, India
W. Scott Goebel, Indiana University School of Medicine, USA
Original Research

In vitro BMP2 stimulation of osteoblast citrate production in concert with mineralized bone nodule formation

Leslie C Costello, Meenakshi A Chellaiah, Jing Zou, Mark A. Reynolds, Renty B Franklin
JRMTE 2015 4 : 2 (17 October 2015)
Abstract | Full text | PDF

Review

Bone marrow mesenchymal stem cells for tissue engineered pulmonary valves (TEPV)

Faizal Z. Asumda, Victor Lamin
JRMTE 2014 3 : 2 (9 January 2014)
Abstract | Full text | PDF

Mesenchymal stem cells

Journal of Regenerative Medicine & Tissue Engineering Open access Journal covers special section Mesenchymal stem cells are stromal cells that are mutipotent which can differentiate into any cell types. This Special section highlights on every aspect of stem cell research like developing methodologies for isolating and culturing MSC'S, Tissue grafting, homing mechanisms, host immune response to implanted cells. It also includes the use of mesenchymal stem cells in the treatment of disorders like cardiovascular diseases, bone and cartilage repair, spinal cord injury and autoimmune diseases.

Biomaterials

Journal of Regenerative Medicine & Tissue Engineering Open access Journal covers special section Biomaterials is a complex system which includes mesoscopic, molecular interactions and their potential applications. This section mainly includes developing new scaffolds for regenerative medicine, cell-materials interface engineering, biomaterials characterization, self-assembled biomimetic copolymers, stem cell therapy and nanomaterials for biosensing applications.

Biomedicine and Drug Delivery

Journal of Regenerative Medicine & Tissue Engineering Open access Journal covers special section Biomedicine is a branch of medical Science that applies biology and other natural-science principles for clinical practice, provides the new ideas for conquering the human health problems. It involves study of (patho-) physiological processes and molecular interactions. This section also attracts drug delivery systems including oral, pulmonary, nasal, parenteral and transdermal, antibody targeting; protein/peptide delivery, DNA, oligonucleotide and siRNA delivery and modes of entry such as controlled release systems, microcapsules, vesicles, liposomes and macromolecular conjugates.

Angiogenesis

Journal of Regenerative Medicine & Tissue Engineering Open access Journal covers special section Angiogenesis is the growth of new blood vessels which plays an important role in the development, reproduction and tissue repair. This section focuses on novel therapeutic approaches for promoting or inhibiting angiogenesis as well as new markers and techniques for disease diagnosis and prognosis.

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