Table 1 : Characteristics of the population studied. Data are presented as means ± SD. BALF: bronchoalveolar lavage fluid. Significant difference from "non-TB" subjects is indicated; * p < 0.05 (Students t-test, unpaired analysis).
| Non-TB Subjects |
Previous TB Infection |
Current TB Infection |
|
| Subjects (n) | 4 | 4 | 3 |
| Mean age (yr) | 52 ± 16 | 51 ± 18 | 40 ± 7 |
| Gender (females; n) | 2 | 2 | 3 |
| Ethnicity (n) | Caucasians 3 Asians 1 |
Caucasians 2 Africans 2 |
Caucasians 2 Africans 1 |
| Current smokers (n) | 0 | 0 | 1 |
| Scar after BCG (n) | 3 | 2 | 0 |
| IGRA (% positive) | 0 | 75 | 100 |
| TB skin test (mm) | 8 ± 5 | 16 ± 5 | 17 ± 3* |
| BMI (kg/m2) | 26 ± 3 | 28 ± 3 | 22 ± 4 |
| Serum-albumin (g/L) | 43 ± 4 | 39 ± 3 | 40 ± 6 |
| Serum 25(OH)D (nmol/L) | 43.0±33.4 | 26.4±30.0 | 17.4±15.6 |
| Radiologic findings | Normal 4 | Possibly inactive 3 Possibly active 1 |
Possibly active 3 |
| Subjects with Cough (n) Haemoptysis (n) Night sweating (n) Heart rate > 100 (n) Fever (> 38 °C, n) Anemia, Hb < 120 (n) |
4 0 0 0 0 0 |
2 0 1 0 0 2 |
1 1 0 1 1 0 |
| BALF cell count (106 cells/L) | 82 ± 10 | 128 ± 62 | 505 ± 235 |
| BALF-macrophages (%) | 93 ± 5 | 90 ± 2 | 86 ± 2 |