Journal of Diabetes Research and Clinical Metabolism

Journal of Diabetes Research and Clinical Metabolism

ISSN 2050-0866
Original Research

Copper is a potent inhibitor of the propensity for human ProIAPP1-48 to form amyloid fibrils in vitro

Christopher Exley1*, Matthew Mold1, Emma Shardlow2, Benjamin Shuker2, Baritore Ikpe2, Ling Wu3 and Paul E Fraser3

*Corresponding author: Christopher Exley c.exley@chem.keele.ac.uk

1. The Birchall Centre, Lennard-Jones Laboratories, Keele University, Staffordshire ST5 5BG, UK.


Journal of Diabetes Research and Clinical Metabolism  2012 1:3doi: 10.7243/2050-0866-1-3

Doi :: 10.1021/ic502945k
Article Title :: Structural Basis for the Inhibition of Truncated Islet Amyloid Polypeptide Aggregation by Cu(II): Insights into the Bioinorganic Chemistry of Type II Diabetes
Journal Title :: Inorganic Chemistry
Author Contributions ::
Lina Rivillas-Acevedo  Carolina Sánchez-López  Carlos Amero  Liliana Quintanar  
Volume :: 54    Issue :: 8    Year :: 2015    eISSN :: 0020-1669
Cited Article
Doi :: 10.1021/acsomega.6b00208
Article Title :: Structure of Spherulites in Insulin, β-Lactoglobulin, and Amyloid β
Journal Title :: ACS Omega
Author Contributions ::
Danielle Cannon  Stephen J. Eichhorn  Athene M. Donald  
Volume :: 1    Issue :: 5    Year :: 2016    eISSN :: 2470-1343
Cited Article
Doi :: 10.1002/chem.201602816
Article Title :: New Insight in Copper‐Ion Binding to Human Islet Amyloid: The Contribution of Metal‐Complex Speciation To Reveal the Polypeptide Toxicity
Journal Title :: Chemistry – A European Journal
Author Contributions ::
Antonio Magrì  Diego La Mendola  Vincenzo Giuseppe Nicoletti  Giuseppe Pappalardo  Enrico Rizzarelli  
Volume :: 22    Issue :: 37    Year :: 2016    eISSN :: 0947-6539
Cited Article
Doi :: 10.1007/s11010-016-2864-1
Article Title :: Receptor-mediated toxicity of human amylin fragment aggregated by short- and long-term incubations with copper ions
Journal Title :: Molecular and Cellular Biochemistry
Author Contributions ::
Giuseppe Caruso  Donatella A. Distefano  Paolo Parlascino  Claudia G. Fresta  Giuseppe Lazzarino  Susan M. Lunte  Vincenzo G. Nicoletti  
Volume :: 425    Issue :: 1-2    Year :: 2017    eISSN :: 0300-8177
Cited Article
Doi :: 10.1016/j.jtemb.2018.09.001
Article Title :: Aggregation of the diabetes-related peptide ProIAPP1-48 measured by dynamic light scattering
Journal Title :: Journal of Trace Elements in Medicine and Biology
Author Contributions ::
Emma Shardlow  Cassandra Rao  Roman Sattarov  Ling Wu  Paul E. Fraser  Christopher Exley  
Volume :: 51    Year :: 2019    eISSN :: 0946672X
Cited Article
Doi :: 10.7243/2050-0866-4-4
Article Title :: Further insight into the role of metals in amyloid formation by IAPP1-37 and ProIAPP1-48
Journal Title :: Journal of Diabetes Research and Clinical Metabolism
Author Contributions ::
Matthew Mold  Chayanit Bunrat  Priya Goswami  Adam Roberts  Charlotte Roberts  Navada Taylor  Hannah Taylor  Ling Wu  Paul E Fraser  Christopher Exley  
Volume :: 4    Issue :: 1    Year :: 2015    eISSN :: 2050-0866
Cited Article
Doi :: 10.1021/acsomega.9b03220
Article Title :: Site-Specific Interactions with Copper Promote Amyloid Fibril Formation for λ6aJL2-R24G
Journal Title :: ACS Omega
Author Contributions ::
Angel E. Pelaez-Aguilar  Gilberto Valdés-García  Leidys French-Pacheco  Nina Pastor  Carlos Amero  Lina Rivillas-Acevedo  
Volume :: 5    Issue :: 13    Year :: 2020    eISSN :: 2470-1343
Cited Article
Doi :: 10.1038/srep01256
Article Title :: Copper prevents amyloid-β1–42 from forming amyloid fibrils under near-physiological conditions in vitro
Journal Title :: Scientific Reports
Author Contributions ::
Matthew Mold  Larissa Ouro-Gnao  Beata M Wieckowski  Christopher Exley  
Volume :: 3    Issue :: 1    Year :: 2013    eISSN :: 2045-2322
Cited Article
Doi :: 10.3390/condmat4010013
Article Title :: X-Ray Absorption Spectroscopy Measurements of Cu-ProIAPP Complexes at Physiological Concentrations
Journal Title :: Condensed Matter
Author Contributions ::
Emiliano De Santis  Emma Shardlow  Francesco Stellato  Olivier Proux  Giancarlo Rossi  Christopher Exley  Silvia Morante  
Volume :: 4    Issue :: 1    Year :: 2019    eISSN :: 2410-3896
Cited Article
Doi :: 10.1016/j.ccr.2012.08.012
Article Title :: Significant omissions of copper-amyloid research in ‘Metal Ions in Neurodegenerative Diseases’ special issue (CCR 256 (19,20) 2012)
Journal Title :: Coordination Chemistry Reviews
Author Contributions ::
Christopher Exley  
Volume :: 256    Issue :: 23-24    Year :: 2012    eISSN :: 00108545
Cited Article
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