Table 1 : Immunopathological classification of RPGN (modified after Szczepiorkowski
et al., [4,6]).
RPGN type | Frequency (%) | |
I | RPGN with linear deposition of IgG due to autoantibodies to type IV collagen representing anti-glomerular basement GN (anti-GBM) | 15 |
1. Goodpasture syndrome 2. Idiopathic anti-GBM nephritis 3. Membranous nephropathy mostly associated with PLA2R antibodies |
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II | RPGN with granular deposits of immune-complexes | 24 |
1. Post-infectious Post streptococcal GN Abscesses Bacterial endocarditis 2. Non-infectious Systemic lupus erythematosus Schönlein-Henoch purpura Cryoglobulinemia Wegner´s granulomatosis Polyarteriitis other forms of vasculitis Solid tumors 3. Primary renal diseases IgG – IgA – nephritis Membranoproliferative GN Idiopathic immune complex nephritis |
||
III | RPGN with or without minimal glomerular deposition (ANCA ab): Pauci-immune Glomerulonephritis | 60 |
1. Microscopic vasculitis 2. Wegner´s granulomatosis 3. Polyarthritis nodosa |
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