Table 1 : Immunopathological classification of RPGN (modified after Szczepiorkowski
et al., [4,6]).


  RPGN type Frequency (%)

I RPGN with linear deposition of IgG due to autoantibodies to type IV collagen representing anti-glomerular  basement GN (anti-GBM)            15

  1. Goodpasture syndrome
2. Idiopathic anti-GBM nephritis
3. Membranous nephropathy mostly associated with
 PLA2R antibodies
 

II RPGN with granular deposits of immune-complexes 24

  1. Post-infectious
Post streptococcal GN
Abscesses
Bacterial endocarditis
2. Non-infectious
Systemic lupus erythematosus
Schönlein-Henoch purpura
Cryoglobulinemia
Wegner´s granulomatosis
Polyarteriitis other forms of vasculitis
Solid tumors
3. Primary renal diseases
IgG – IgA – nephritis
Membranoproliferative GN
Idiopathic immune complex nephritis
 

III RPGN with or without minimal glomerular deposition (ANCA ab): Pauci-immune Glomerulonephritis 60

  1. Microscopic vasculitis
2. Wegner´s granulomatosis
3. Polyarthritis nodosa
 

Bambauer et al.Clinical Nephrology and Urology Science  2014 1:2DOI : 10.7243/2054-7161-1-2