Table 6 : Literature review of intracranial meningiomas in children and young adults.


Authors Age
group
Time
period
(years)
# of
Patients
Seizure Motor
deficit
CN
palsy
Raised
ICP
Headache Loss of
vision
Ataxia Syndrome Previous
Radiation

Germano,
1994
0-20y 42 23 25% 33% NS 25% NS NS NS NF (3) 2
Erdingler,
1998
0-15y 26 29 NS 21% 14% 41% NS NS NS NF1 (7),
NF2(5)
NS
Rushing,
2005
0-20y 22 87 33% 10% NS NS 13% NS 10% NF2(9),
Gorlin(2),
Down (1)
7
Gao, 2009 0-18y 15 54 35% 22% 26% 30% 37% 22% 6% NF2 (5) 0
Menon,
2009
0-20y 27 38 76% 39% 13% 71% NS 34% NS NF1 (8),
NF2 (3)
1
Thuijs,
2012
0-18y 35 72 28% NS NS 36% NS NS NS NF2(13) 4
Santos,
2012
0-18y 16 15 20% NS NS 20% 40% NS NS NF2 (5) 6
Ravindranath,
2013
0-18y 24 31 36% 36% 9% 32% NS 6% NS NF1 (2),
NF2(2)
NS
LUMC,
2013
0-30y 30 35 26% 9% 6% NS 46% 20% NS 0 5

Authors Supratentorial Infratentorial Multiple GTR WHO I WHO II   WHO III F/U Recurrence Good
Outcome

Germano,
1994
70% 13% NS 60% 71% 29%   - 12.9y 0 100%
Erdingler,
1998
81% 19% 7% 86% 94% 3%   3% 6.5y NS NS
Rushing,
2005
76% 16% NS 62% 71% 24%   5% 6.5y 19% NS
Gao,2009 70% 28% NS 72% 82% 11%   7% 5y 30% 82%
Menon,
2009
49% 32% 7% 49% 73% 22%   5% 5y 18% 84%
Thuijs,2012 58% 18% 6% 55% 74% 18%   8% 5y 26% 5y PFS 56%,
OS 84%
Santos, 2012 50% 17% 20% 80% 73% 27%   - 5y 33% 80%
Ravindranath,
2013
51% 49% 6% 83% 64% 36%   - 4y 64% 81%
LUMC,
2013
71% 29% 9% 48% 73% 16%   10% 6.5y 12% NS

ICP: Intracranial pressure, GTR: Gross total resection.

Prabhu et al.Neuroscience Discovery  2014 2:1DOI : 10.7243/2052-6946-2-1