Table 6 : Literature review of intracranial meningiomas in children and young adults.
Authors | Age group |
Time period (years) |
# of Patients |
Seizure | Motor deficit |
CN palsy |
Raised ICP |
Headache | Loss of vision |
Ataxia | Syndrome | Previous Radiation |
Germano, 1994 |
0-20y | 42 | 23 | 25% | 33% | NS | 25% | NS | NS | NS | NF (3) | 2 |
Erdingler, 1998 |
0-15y | 26 | 29 | NS | 21% | 14% | 41% | NS | NS | NS | NF1 (7), NF2(5) |
NS |
Rushing, 2005 |
0-20y | 22 | 87 | 33% | 10% | NS | NS | 13% | NS | 10% | NF2(9), Gorlin(2), Down (1) |
7 |
Gao, 2009 | 0-18y | 15 | 54 | 35% | 22% | 26% | 30% | 37% | 22% | 6% | NF2 (5) | 0 |
Menon, 2009 |
0-20y | 27 | 38 | 76% | 39% | 13% | 71% | NS | 34% | NS | NF1 (8), NF2 (3) |
1 |
Thuijs, 2012 |
0-18y | 35 | 72 | 28% | NS | NS | 36% | NS | NS | NS | NF2(13) | 4 |
Santos, 2012 |
0-18y | 16 | 15 | 20% | NS | NS | 20% | 40% | NS | NS | NF2 (5) | 6 |
Ravindranath, 2013 |
0-18y | 24 | 31 | 36% | 36% | 9% | 32% | NS | 6% | NS | NF1 (2), NF2(2) |
NS |
LUMC, 2013 |
0-30y | 30 | 35 | 26% | 9% | 6% | NS | 46% | 20% | NS | 0 | 5 |
Authors | Supratentorial | Infratentorial | Multiple | GTR | WHO I | WHO II | WHO III | F/U | Recurrence | Good Outcome |
||
Germano, 1994 |
70% | 13% | NS | 60% | 71% | 29% | - | 12.9y | 0 | 100% | ||
Erdingler, 1998 |
81% | 19% | 7% | 86% | 94% | 3% | 3% | 6.5y | NS | NS | ||
Rushing, 2005 |
76% | 16% | NS | 62% | 71% | 24% | 5% | 6.5y | 19% | NS | ||
Gao,2009 | 70% | 28% | NS | 72% | 82% | 11% | 7% | 5y | 30% | 82% | ||
Menon, 2009 |
49% | 32% | 7% | 49% | 73% | 22% | 5% | 5y | 18% | 84% | ||
Thuijs,2012 | 58% | 18% | 6% | 55% | 74% | 18% | 8% | 5y | 26% | 5y PFS 56%, OS 84% |
||
Santos, 2012 | 50% | 17% | 20% | 80% | 73% | 27% | - | 5y | 33% | 80% | ||
Ravindranath, 2013 |
51% | 49% | 6% | 83% | 64% | 36% | - | 4y | 64% | 81% | ||
LUMC, 2013 |
71% | 29% | 9% | 48% | 73% | 16% | 10% | 6.5y | 12% | NS | ||
ICP: Intracranial pressure, GTR: Gross total resection.