Journal of Eye and Ophthalmology

Journal of Eye and Ophthalmology

ISSN 2055-2408
Case report

Long standing exophytic conjunctival papilloma infected with human papillomavirus

Anvesh Annadanam1, M. Adelita Vizcaino2, Charles George Eberhart2, Gibran S. Khurshid3 and Praveena Gupta4*

*Correspondence: Praveena Gupta

4. Department of Ophthalmology and Visual Sciences, University of Texas Medical Branch, Galveston, TX, USA.

Author Affiliations

1. Wilmer Eye Institute, Johns Hopkins University, Baltimore, MD, USA.

2. Department of Pathology, Johns Hopkins University, Baltimore, MD, USA.

3. Department of Ophthalmology, University of Florida, Gainesville, FL, USA.


Background: Most conjunctival papillomas are benign in nature. However, any long standing conjunctival mass should not evade the surveillance of carcinogenicity. Presented here is a case of a long standing conjunctival papilloma (HPV) that showed the presence of low risk human papillomavirus based on histological testing.

Methods: This is a retrospective review of a case of a patient with a longstanding conjunctival mass that was surgically excised. Baseline demographics, ocular history, and pathology reports are presented.

Results: A 48-year-old man presented for urgent care evaluation of a growth on his left lower eyelid that was itchy and bled intermittently with eye rub. Ocular examination of the lower eyelid revealed a large pink pedunculated mass on the palpebral conjunctiva. The patient underwent excision of the mass with conjunctivoplasty and ocular surface reconstruction. Histopathology of the tissue revealed the mass to be a conjunctival papilloma with positive staining for low-risk HPV types 6 and 11.

Conclusion: Although the chronic nature of the lesion reduces malignant potential, staining for low risk HPV 6 and 11 was present. Any longstanding papilloma warrants histopathology workup to help with appropriate medical or surgical management.

Keywords: Conjunctival papilloma, human papillomavirus, exophytic papilloma, conjunctival mass, conjunctiva

ISSN 2055-2408
Volume 4
Abstract Download