Pathology Discovery

Pathology Discovery

ISSN 2052-7896
Case report

Primary adenoid cystic carcinoma in the peripheral lung: a cytological, histopathological and immunohistochemical report of two cases

Fumimasa Etori1, Naoki Watanabe1, Masashi Matsuyama1, Naomi Kawaguchi1, Asuka Sekiya1, Kyoko Nambu1, Toshimasa Sakakima2, Toshiyuki Sawa3, Tsutomu Marui4, Takafumi Naiki2 and Takuji Tanaka1*

*Correspondence: Takuji Tanaka takutt@gmhosp.gifu.gifu.jp

1. Department of Diagnostic Pathology (DDP) & Research Center of Diagnostic Pathology (RC-DiP), Gifu Municipal Hospital, 7-1 Kashima-cho, Gifu City, Gifu 500-8513, Japan.

Author Affiliations

2. Department of Central Laboratory, Gifu Municipal Hospital, 7-1 Kashima-cho, Gifu City, Gifu 500-8513, Japan.

3. Oncology Center, Gifu Municipal Hospital, 7-1 Kashima-cho, Gifu City, Gifu 500-8513, Japan.

4. Department of Respiratory Surgery, Gifu Municipal Hospital, 7-1 Kashima-cho, Gifu City, Gifu 500-8513, Japan.

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Abstract

Primary adenoid cystic carcinoma (ACC) of the peripheral lung is a rare entity. Here we report two cases of primary ACC. Case 1 is an 84-year-old male with a past-medical history of cecal cancer presented with a 10 mm left upper lung nodule. Case 2 is a 40-year-old female who presented with 30 mm right upper lobe. Intraoperative (Case 1) and pre-operative (Case 2) histopathologic and cytologic diagnoses were consistent with a primary peripheral lung ACC. An upper lobectomy┬▒mediastinal lymph node dissection was performed and immunohistochemical staining with thyroid transcription factor (TTF)-1, c-KIT, and MYB on the excision specimen confirmed our diagnosis.

Keywords: Adenoid cystic carcinoma, lung, cytology, immunohistochemistry, case reports

ISSN 2052-7896
Volume 3
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