Pathology Discovery

Pathology Discovery

ISSN 2052-7896
Original Research

IgG4-Related orbital disease in patients with diabetic retinopathy: Effects of glucan and vitamin D supplementation

Richter Josef1, Závorková Martina2, Vetvicka Vaclav1*, Král Vlastimil1, Stiborova Ivana1, Liehneová Ivana1 and Pohořská Jitka1 and Rajnohova Dobiasova Lucie1

*Correspondence: Vetvicka Vaclav

1. Zdravotní ústav se sídlem v Ústínad Labem, Usti nad Labem, Czech Republic, Europe.

Author Affiliations

2. Oční klinika UJEP Masarykovanemocnice, Krajskázdravotní, a.s., Usti nad Labem, Czech Republic, Europe.


Background: Diabetic retinopathy represents a serious complication of diabetes.

Methods: In our group of 52 patients, we identified 7 individuals (13%) with elevated levels of IgG4.

Results: Detailed examination revealed significant clinical changes, resulting in a diagnosis of probable IgG4-RD.

Conclusions: Long-term evaluation and beta glucan supplementation, combined with vitamin D supplementation, during general treatment of these patients significantly improved both health and mental conditions.

Keywords: IgG, IgG4-RD, glucan, vitamin D

ISSN 2052-7896
Volume 6
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