Table 1 : Change in body composition and disease activity following disease ‘flare’ and subsequent treatment with
intramuscular injection of corticosteroid (triamcinolone acetonide).


  Assessment 1
(56 days pre-CI)
Assessment 2
(28 days post-CI)
Change:
Assessment 1-2 (%)
Assessment 3
(86 days post-CI)
Change:
Assessment 2-3 (%)

ALM (kg) 29.4 27.4 -2.0 (-7%) 27.8 +0.4 (+2%)
TLM (kg) 66.1 63.7 -2.4 (-4%) 64.0 +0.3 (+1%)
TFM (kg) 22.0 21.6 -0.4 (-2%) 21.6 0 (0%)
Body fat (%) 24.2 24.5 +0.3 (+1%) 24.5 0 (0%)
DAS28 score: 2.91 1.54 -1.37 (-47%) NRb NR
■ CRP (mg/l) 8 <5a NR NR NR
■ Tender joints (n) 1 0 -1 NR NR
■ Swollen joints (n) 1 0 -1 NR NR
■ VAS (1-100) 23 0 -23 NR NR

CI: Corticosteroid injection (40mg triamcinolone acetonide); ALM: Appendicular lean mass (muscle of arms and legs);
TLM: Total lean mass; TFM: Total fat mass; DAS28: Disease Activity Score in 28 joints (not measured at Assessment 3);
CRP: blood C-reactive protein level; VAS: Visual analogue scale for global health; NR: Not reported. a: CRP at
‘Assessment 2’ fell below detectable range (<5 mg/l); b: no measure of DAS28 was made at ‘Assessment 3’

Wilkinson et al.Journal of Rheumatology and Orthopedics  2015 2:2DOI : 10.7243/2055-7000-2-2