Table 3 : Result of endocrine disruptor classification in relation to the
different options under discussion on basis of EATS related effects.


Substance EU-Option 2 EU-Option 3 EU-Option 4 Industry Proposal

Sucrose Not classified Not classified Not classified Not classified

Genistein Endocrine
Disruptor
Endocrine
Disruptor Cat. 1
Endocrine
Disruptor
Endocrine
Disruptor

Caffeine Endocrine
Disruptor
Endocrine
Disruptor Cat. 1
Not classified Not classified

Vitamin D3 Not classified Endocrine Active
Substance  Cat. 3*
Not classified Not classified

*classification due to single in vitro findings on influences on aromatase activity

Schuhmacher-Wolz et al.Journal of Toxicology and Health  2017 4:2DOI : 10.7243/2056-3779-4-2