Table 1 : Liposomal formulations.

Formulation code	Composition	Preparation technique	Sirolimus dose (mg/mL)
HM16	Lecithin : Cholesterol (6:1 molar ratio) Sucrose 8.7 %	Modified heating method	0.16
HM4			0.4
Empty	Lecithin : Cholesterol (6:1 molar ratio)	Ethanol injection	0
EI16			0.16
EI4			0.4

HM16: Liposomes loaded with 0.16 mg/ml of sirolimus by the modified heating method.
HM4: Liposomes loaded with 0.4 mg/ml of sirolimus by the modified heating method.
EI16: Liposomes loaded with 0.16 mg/ml of sirolimus by etanol injection.
EI4: Liposomes loaded with 0.4 mg/ml of sirolimus by etanol injection.