Table 3 : Indicators of ocular irritation with significant difference after treatment.

Technique	Parameter of the McDonald-Shadduck scoring system	Formulation			ANOVA p-value	Tukey-Kramer p-value
		Empty (A)	0.16 mg/ml (B)	4 mg/ml (C)
Modified heating method	Vision Clarity	1.44±1.04	0.88±1.24	1.71±1.43	<0.05	B vs C < 0.05
	Corneal Vascularization	1.40±0.58	0.40±0.50	0.91±0.85	< 0.001	A vs B <0.01 A vs C <0.05 B vs C < 0.05
	Conjunctival Discharge	1.68±1.14	0.60±0.65	0.94±1.00	< 0.001	A vs B <0.01 A vs C < 0.05
Ethanol injection	Vision Clarity	1.94±1.24	2.49±1.31	0.65±0.75	<0.001	A vs C <0.01 B vs C <0.01
	Corneal Vascularization	1.42±0.91	0.66±0.48	0.90±0.31	<0.001	A vs B <0.01 A vs C <0.05
	ConjunctivalDischarge	1.75±1.18	0.97±1.04	1.10±1.25	<0.02	A vs B < 0.05

Data is average ± standard deviation