Veterinary Medicine and
Animal Sciences

Veterinary Medicine and Animal Sciences

ISSN 2054-3425
Original Research

Maintenance of Pregnancy in Beef Cattle after a Luteolytic Dose of ProstaglandinF

C. Edward Ferguson1*, Darrel J. Kesler2 and Robert A. Godke3

*Correspondence: C. Edward Ferguson

1. Department of Agricultural Sciences, McNeese State University, Lake Charles, LA.

Author Affiliations

2. Department of Animal Sciences, University of Illinois, Champaign-Urbana, IL.

3. Department of Animal Sciences, Louisiana State University, Baton Rouge, LA.


The increased use of assisted reproductive technologies (ARTs), increase the risks of erroneous prostaglandin F (PGF) administration. The objective of this study was to determine if pregnancies could be maintained if P4 was administered after PGF administration. A total of seven pregnant heifers between 30 - 40 days of gestation and 19 pregnant cows between 30 to 40 (n=12) or 80 to 90 (n=7) days of gestation were used. All females were administered a maintenance dose of P4 or progestin at either 2, 6, 8, 10, 12 or 18 hours post-PGF for 7 days. A total of 18 of 25 (72%) pregnancies were maintained for a minimum of 7 days. The success rate for cows and heifers receiving P4 or progestin 2, 6, 10, 12 or 18 hours after PGF was 4/6 (75%), 6/6 (100%), 2/3 (67%), 2/4 (50%), 1/2 (50%) and 3/4 (75%), respectively. Maintenance P4 or progestin was continued on selected females (12 of the 18) and they were examined via ultrasonography 2 to 3 times weekly until a follicle ≥10 mm developed on the ovary ipsilateral to the gravid uterine horn, at which time hCG (2,500 IU) was administered. Luteal tissue was successfully induced in 10 of the 12 (83%) and 8 of these calved (80%). These results indicate that it is possible to maintain a bovine pregnancy by administering maintenance dose of P4 from 2 to 18 hours post-PGF.

Keywords: Cattle, abortion, induced luteal tissue, pregnancy, progesterone

ISSN 2054-3425
Volume 2
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