Figure 1 : The Varicella Zoster Virus life cycle.

The varicella zoster virus (Vzv) enters the body through the respiratory tract epithelium
(RtE). From here it infects the mononuclear cells (MnC), especially T-cells that carry the
virus to the lymphoreticular tissues (LrT) where it replicates. In association with the MnC
the virus enters the blood stream causing viremia and is seeded out to epithelial sites
(Ep) creating chickenpox (Cp). The mucocutaneous lesions heal but the virus enters
sensory nerve endings, is transported via the peripheral nerve to the sensory ganglia
and a latent infection is established. Later in life a secondary infection can occur causing
zoster or shingles (Sh) in the dermatome at the site of reactivation.

Rasmussen et al.Virology Discovery  2014 2:1DOI : 10.7243/2052-6202-2-1